What this result means
Choose whether the laboratory result is serum or plasma total folate, or an already calculated red-cell folate result. Then choose the units and enter the reported number. The converter uses 1 ng/mL = 1 µg/L = 2.265 nmol/L. [1][3][4][5]
The concentration stays the same
Keep the specimen attached to the number
WHO treats serum or plasma folate and red-cell folate as distinct measures. They cannot be converted into one another with a unit factor. Choose red-cell folate only when the source report already gives the final red-cell concentration; laboratory calculation from whole blood may require haematocrit and other assay information. [2][4][5]
Why this version uses 2.265
CDC data documentation and current laboratory guides use 2.265 for total folate reported as a folic-acid equivalent. This calculator pins that factor so every conversion is reproducible and the reverse calculation uses the exact reciprocal 200/453. [1][3][4][5]
The factor does not apply to every folate molecule separately. CDC laboratory documentation lists different conversion factors for individual folate forms, so this tool accepts only a laboratory total-folate result reported under the conventional factor. [6]
How the answer is rounded
The calculator stores 2.265 as the exact fraction 453/200, uses 200/453 for the reverse, and rounds only the final display. It shows one decimal in nmol/L and two decimals in ng/mL or µg/L. These display digits explain the arithmetic but do not add precision to the source laboratory measurement. [1][3]
What the conversion cannot tell you
The converted number does not classify folate status, diagnose a deficiency or show what caused a result. Reference intervals, clinical decisions and pregnancy or treatment guidance are separate questions that depend on the original report, assay, health context and qualified professional advice. [2]
Safe next steps
Check the source report for the specimen, analyte name, original unit, assay note, reference interval and date. Keep those details beside the converted value. If the report names a specific folate form, supplies a whole-blood intermediate or uses a different stated factor, do not use this converter; follow the laboratory's own method information. [4][5][6]
Formula and assumptions
- Formula
- nmol/L = ng/mL × 2.265; ng/mL = nmol/L × 200 ÷ 453. One ng/mL equals one µg/L, so the same equations apply to µg/L. The specimen context never changes the arithmetic. [1][3][4][5]
- Version
- Total folate reporting-unit conversion, folate-folic-acid-equivalent-conversion-v1
- Rounding
- Use exact decimal arithmetic with 2.265 stored as 453/200 and its reciprocal as 200/453, then round once: one decimal for nmol/L and two decimals for ng/mL or µg/L. Exact halfway ties round upward in magnitude; a positive value below display resolution uses a less-than result.
Who this is for — and when not to use it
Intended use
Neutral unit conversion for a person who already has a laboratory total folate concentration reported as serum, plasma or a final red-cell result in ng/mL, µg/L or nmol/L.
Not intended for
This tool does not interpret folate status, apply a deficiency threshold or reference range, diagnose a condition, convert between serum or plasma and red cells, calculate red-cell folate from whole blood and haematocrit, convert an individual folate form, or guide food, supplement, pregnancy or treatment dosing.
Exclusions
- Folate-status interpretation, deficiency thresholds, reference ranges, targets and diagnosis
- Conversion between serum or plasma folate and red-cell or erythrocyte folate
- Whole-blood or haemolysate calculations requiring haematocrit or another laboratory input
- Individual folate forms or vitamers, including 5-MTHF, 5-formylTHF, THF, unmetabolised folic acid and MeFox
- Food folate, dietary folate equivalents, supplement labels, microgram doses and treatment dosing
- MTHFR interpretation, pregnancy advice, symptoms, medication decisions or urgent-care decisions
- Any analyte other than laboratory total folate
- Changing or reconstructing precision absent from the original laboratory report
Evidence sources
- 1. NHANES 2015–2016 Data Documentation: Folate Forms — Total and Individual — National Center for Health Statistics, Centers for Disease Control and Prevention. Accessed Aug 17, 2026.
- 2. Serum and Red Blood Cell Folate Concentrations for Assessing Folate Status in Populations — World Health Organization. Accessed Aug 17, 2026.
- 3. Auckland Test Guide: Folate — Te Toka Tumai Auckland, Te Whatu Ora. Accessed Aug 17, 2026.
- 4. Folate, Serum/Plasma — In-Common Laboratories. Accessed Aug 17, 2026.
- 5. Folate, Erythrocytes — In-Common Laboratories. Accessed Aug 17, 2026.
- 6. NHANES 2015–2016 Laboratory Procedure Manual: Folate Forms — National Center for Health Statistics, Centers for Disease Control and Prevention. Accessed Aug 17, 2026.